How Men from Deprived Areas in the UK are Profiting Immensely from an Effective Bowel Screening Programme

Areas, Bowel, Deprived, Effective, Immensely, Men, Profiting, Programme, Screening

SEO Friendly News Article

The Effectiveness of Bowel Cancer Screening Programme: A Study Reveals Benefits for Men in Deprived Areas

Figure 1: Diagnosed incident cases of CRC in both sexes in the UK, all ages ≥18 years, 2023–2031. Source: GlobalData.

The Bowel Cancer Screening Programme (BCSP)

The Bowel Cancer Screening Programme (BCSP) was introduced in England in 2006 with the intention of lowering colorectal cancer (CRC) incidence and mortality. The program initially involved sending a biennial guaiac faecal occult blood test (gFOBT) to everyone aged 60 to 69 years; this age range was later extended to include 70 to 74-year-olds in 2010 to reflect the increasing life expectancy.

CRC Incidence and Mortality in the UK

CRC is the second most common cause of death in the UK; it has a long lag period of ten to 15 years from which an initial polyp develops into a cancerous tumor. Secondary prevention through screening programs such as BCSP can reduce the CRC mortality rate by identifying and removing precancerous lesions before they reach the advanced stage of the disease. The diagnosed incident cases of CRC in the UK alone are predicted to reach just over 42,000 by the end of 2023 and over 53,000 by the end of 2031 by GlobalData epidemiologists (Figure 1).

Quantifying the Effectiveness of BCSP

However, the effectiveness of the BCSP in reducing the CRC incidence rate since its rollout in 2006 has not yet been quantified. So, Granger and colleagues conducted a 2023 population-based study published in Colorectal Disease, looking at the temporal trends in CRC incidence by tumor location, gender, and socioeconomic status from 2001 to 2017, and found that the screening program benefited men from deprived areas.

The Study Findings

  • A total of 541,515 incident cases of CRC from 2001 to 2017 in people aged 60–74 years were identified using the National Cancer Registration and Analysis Service (NCRAS).
  • The overall trend in CRC age-standardized incidence rates (ASIR) for both proximal and distal CRC was higher in men than women throughout the study period.
  • Since 2008, the ASIR in men has reduced considerably more than in women, with a negative APC of 2.1% and 1.1%, respectively.
  • There was an increasing ASIR in men and women for distal tumors from 2001–2010 for men and 2001–2011 for women.
  • Men from deprived areas saw the most benefits from the BCSP, with a statistically significant reduction in the ASIR of proximal tumors from 2008 onwards.

Impact of BCSP on Men from Deprived Areas

Men benefited the most from the screening program, even though the uptake was lower compared to women. The general increase in incidence after the initial introduction of BCSP can be explained by the identification of previously undiagnosed CRC cases. The subsequent decline in ASIR of CRC can then be explained by the identification of potentially cancerous lesions, which were then removed. The study highlighted groups that benefited the most from BCSP: men from deprived areas and those with distal tumors. This study has not only quantified the effectiveness of the BCSP but also provided helpful information for public health officials on the demographic that needs more encouragement for participation.

Leave a Comment